What is a knockout mouse?

Learn how scientists use mouse models to understand how our genes contribute to biology and disease.

About the video

Learn how scientists use mouse models to understand how our genes contribute to biology and disease.

Understanding the exact role a gene plays in biology or disease is challenging because multicellular organisms, like humans, are complex. Just over thirty years ago a group of scientists made a pivotal discovery that led to the development of an important tool that changed the way scientists could study the role of a single gene and its impact on an entire biological system: the knockout mouse.

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